A modular zinc finger adaptor accelerates the covalent linkage of proteins at specific locations on DNA nanoscaffolds.

نویسندگان

  • Eiji Nakata
  • Huyen Dinh
  • Tien Anh Ngo
  • Masayuki Saimura
  • Takashi Morii
چکیده

A modular adaptor consisting of a sequence-specific DNA binding zinc finger protein and a self-ligating protein-tag was developed to expedite efficient formation of a covalent linkage between an individual protein molecule and the programmed address modified with a tag-substrate on the DNA nanostructure.

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عنوان ژورنال:
  • Chemical communications

دوره 51 6  شماره 

صفحات  -

تاریخ انتشار 2015